DPCstruct | MC42094

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)148 ± 18 aa
Standard deviation of domain lengths17.95
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score90.67
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)39.01
Pfam Score100.00
Assigned Pfam label(s) CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A496M2X0 123-294 IDEAIEKGSNLHDLADYAVIQINDTHPSLVIPEMIRLLTERGLDLDEAIAIVQKMTAYTNHTILAEALEKWPLEFLKEVVPHLVPII…
A0A447TTG7 1-141 MNDTHPTIAIPELLRVLIDEHQLSWDDAWAITSKTFAYTNHTLMPEALECWDEKLVKALLPRHMQIIKQINDRFKTLVDNTWPGDKQ…
A0A7J7GWT1 124-251 None
A0A814K3D9 377-532 None
A0A4S4EB45 220-389 None
A0A357B459 111-245 None
A0A6A4V0U7 259-392 None
A0A643C449 671-818 None
A0A2P4SCN2 112-250 None
A0A0G0PRV0 179-302 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.