DPCstruct | MC42062

Metacluster Properties and Pfam Annotations

Number of structural domains90
Mean domain length (aa)149 ± 38 aa
Standard deviation of domain lengths37.96
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.50
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)21.44
Pfam Score98.98
Assigned Pfam label(s) PF12014- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S2JB64 1-147 GLFTADYGVHGPEVIEVRLARLHSDAPTYELVGIKLTGDRHVPAGQRTWSAALPKEPSTHSPHPCLGAPSASAPQGAQLPSQSAALI…
A0A1Z5KQN3 171-297 GLWVGRYGNHGFEMINITYAGDTMIAYKVTDNDNVPSGEVSFTVDLSPNPKTIHGETPLLEPIELNHDAAEQWGLKYLPRFTGRGQV…
A0A3L6PPE1 370-520 None
A0A2S4UK84 351-513 None
B7G3D6 218-346 None
Q2GQA2 25-188 None
M8B160 1-174 None
A0A1D6GL50 171-264 None
A0A5K1JVG2 147-271 None
A9T024 2-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.