DPCstruct | MC42052

Metacluster Properties and Pfam Annotations

Number of structural domains209
Mean domain length (aa)139 ± 21 aa
Standard deviation of domain lengths21.28
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score90.12
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)30.04
Pfam Score99.28
Assigned Pfam label(s) PF00330- CL0159- CL0364

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V5NDJ8 248-399 AASIWATGRTWWQIPPIAKVTFSGVLPVGVTGKDVIVALCGLFNNDEVLNHAIEFTGSEQTMRSIPVDDRLAIANMTTEWGALSGLF…
A0A6D0EK43 69-213 LNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKG…
A0A7M3RRE8 329-470 None
A0A377D2L5 103-259 None
A0A1M7PF56 139-284 None
A0A7C7PDK4 94-233 None
A0A4S4D064 254-333 None
A0A3Q0JB04 122-266 None
A0A835HGM6 13-125 None
A0A850R341 49-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.