DPCstruct | MC42022

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)92 ± 13 aa
Standard deviation of domain lengths12.81
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score89.63
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)40.79
Pfam Score100.00
Assigned Pfam label(s) CL0032

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S9YKQ3 25-119 DAHIRLAAPRRGAGEEMLRRSYSYSIGQESGAAGDEDAGLIFVSYQADPTTSFIPVQQRLAKSDALAHFTLATSSALFAILPGVVGR…
A0A484XBG1 152-234 DVPYYARDPQGDVIALDSHIRLANPRTPETQSSLMMRRGYSYSLGVTNAGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEE
A0A1P8XM99 2-81 None
A0A4V3IW56 11-87 None
A0A6S7BHR8 1-100 None
A0A379FIU8 18-107 None
A0A378F898 670-752 None
A0A806J384 32-121 None
A0A7C6XK46 9-83 None
A0A285V478 274-373 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.