DPCstruct | MC42017

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)82 ± 10 aa
Standard deviation of domain lengths9.78
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score94.62
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.21
Pfam Score87.50
Assigned Pfam label(s) CL0179- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A845RVF0 1-70 YTGTMCVEFFVTRKNELLVNEIAPRVHNSGHLTMNAHNVSQFENHIRAVCNLKLIKPKRIHKAIMYNILG
A0A7Y1X380 1-82 MQSTFPGCGIFGVEMFYLETGELLINEIAPRPHNSGHYTIDACVTSQFEAHLRSILDLPMPKNFTSFSTITTNAIMLNVLGD
F9DEA1 28-116 None
A0A4U0XDE6 429-532 None
A0A287KIE9 1-101 None
A0A536C0G7 430-504 None
A0A840R914 5-76 None
N1U980 8-90 None
A0A6P5UIJ7 443-517 None
A0A812PN94 90-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.