DPCstruct | MC42008

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)106 ± 16 aa
Standard deviation of domain lengths16.48
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score88.67
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)46.03
Pfam Score100.00
Assigned Pfam label(s) PF00940

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M3VJR5 2-96 ESQRAVDAAAGMPVAQALEGFVQRKVIKQSVMTTVYGVTLYGAMAQIRRQLKEIPEFPRERWLGPASAYLARLTLASISAIFTSSSE…
A0A1D6IJW8 58-204 YTGIANRVMEIMRMDAQKDPSVEPDAARARLIVDQVDRKLVKQTVMTSVYGVTYIGAREQIRRRLKERGVIPNDSELFGASCYAAKV…
A0A183WN36 99-192 None
S4RK49 749-877 None
M1V872 982-1082 None
A0A445CUN6 13-94 None
A0A0V0YC22 350-457 None
A0A367YHJ4 70-199 None
A0A7G2CKF4 870-1014 None
A0A6P6BMJ6 539-634 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.