DPCstruct | MC42006

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)103 ± 11 aa
Standard deviation of domain lengths11.10
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score77.23
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)39.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U5ME32 150-228 LTVDEKELLKNQNGGLQTFLKNHHQIFKVIGGKVKIKNWREELELAPLKKNHVKKSECWFLRNHPDGCPLSEETCRFAH
A0A504YBI1 1-95 MKSQHGGLQTLLKNHHQAFEIRSGLIRLRFDPERMAQLNPSGGSFVLRKPAKKRLIHRKTKPCWMFSHHVDGCPYPSETCDFLHKTE…
A0A2C9K731 482-609 None
A0A0R3T7M4 558-664 None
A0A4Y1ZXK7 92-211 None
A0A5E4C7L4 469-569 None
A0A182WBK6 523-638 None
A0A0V0X5J0 678-779 None
A8P0B4 216-316 None
A0A6P4WEU0 554-660 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.