DPCstruct | MC42000

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)226 ± 17 aa
Standard deviation of domain lengths16.86
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.68
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)24.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A8RG54 3-268 LADRLLGMVVRGFDYLPVVDVTFGDVVRATVTADRRLYPEDRQHLRSMLVEAFRRRGIWPKNVTSLTDDALVWVQPDSGLQLTGSVD…
A0A3S9DWL2 336-554 IAIQALDLLPPVEVTFNDYARAVLRNLAIADPTDPHGYRKMIADIFVAREIISCDEGKALLEPAPLYDRMPGAIAHDPELIGSSRAE…
A0A7C1DSD9 591-857 None
A0A1Q6X450 12-215 None
A0A7Y0PAR4 892-1112 None
A0A1M6IG93 952-1173 None
B4WCZ3 798-1040 None
A0A7V9NI35 48-267 None
A0A857JDX4 403-620 None
Q2IGE8 721-957 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.