DPCstruct | MC42

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)136 ± 14 aa
Standard deviation of domain lengths13.56
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.20
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)16.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X9HBE2 60-171 IQYLGGFLLSTNGDDSFGIEQYLSSNKRFLMLFTGKHLIRDVLEIDKKELENRILTEYCITKNGLETEIIALVNPTETEFHTKIIKA…
A0A372DT27 12-153 RGWVGKIVPPYPDGVVETAGSCIGDPAAAPAALCDHAIAVLHDPQSGLRTILALTQAPHFGKQPLWRIADALEPGELDDRGVEVATA…
A0A351L4E8 76-207 None
A0A095V088 31-166 None
A0A246FG97 9-144 None
K9PU90 9-170 None
A0A5B7R0C6 284-435 None
A0A6I4IVU6 16-150 None
A0A3A6P6A7 34-168 None
A0A7Y7NXP8 108-253 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.