DPCstruct | MC41998

Metacluster Properties and Pfam Annotations

Number of structural domains280
Mean domain length (aa)210 ± 44 aa
Standard deviation of domain lengths43.58
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.22
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)15.25
Pfam Score94.59
Assigned Pfam label(s) CL0023- PF14332- CL0304

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3F2U3S5 3-222 QELAQAAVTTRTGVLRVTGEPGGDLHVVHGLVVTVDSPGAPGVRELLARPGRTTTGAAELEVVAMMAAIDGCFAIASGWIGSCFWQA…
A0A221T3I9 3-167 KGPLSDVSLISILMLLRENKHSGVLHVNSDVPMTMTLSSGELIDGCVLDWTGLEAVQTTPLDPNVGHFHFVKGDVEGEPLGFFDAVI…
A0A538Q002 4-257 None
A0A7C5J2U3 675-891 None
B9XDL9 280-541 None
A0A2Z4FMR3 161-347 None
A0A348XFN2 130-311 None
A0A656HFC2 2-124 None
A0LIT0 125-309 None
A0A523DYR3 3-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.