DPCstruct | MC41993

Metacluster Properties and Pfam Annotations

Number of structural domains563
Mean domain length (aa)103 ± 21 aa
Standard deviation of domain lengths21.11
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.14
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.23
Pfam Score99.45
Assigned Pfam label(s) CL0123- CL0004- CL0302

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A426TSN1 4-88 QRTYTIRVAAQLAGLHEQSLRAYERRGLINPARSKGNIRRFSDADLEQIRFIKRLVDDLGVNLAGVEVIIQLRHQLLEAHRELHE
A0A538L9E3 19-94 LDKVELYLGQVCQIAGISKMQLDYWTNKAQIPTKGKKQRIYDIDALETVMLIKQAKDKGLNLGAAIDAARRFREQN
A0A1M3FCM7 1-110 None
A0A1Q6Y6L2 1-128 None
A0A4Q5IXX1 2-67 None
A0A378B105 124-238 None
A0A7C5YNL6 3-87 None
M1TV07 35-166 None
A0A2V9TM61 1-87 None
A0A7C4LWY6 93-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.