DPCstruct | MC41892

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)67 ± 8 aa
Standard deviation of domain lengths7.89
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score73.01
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)57.69
Pfam Score94.60
Assigned Pfam label(s) CL0125- PF00566- CL0214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P6GC96 6-70 VNKKLLEELEGMGFPTARATRALHYSGNSSLEAAVNWVVEHENDTDIDEMPMVPASTKVEASKPS
A0A251TEY1 1-58 MDVEGVNKKLVDELEEMGFPLPRAMRALYYSGNSSLEDAINWIVDHEDDPDIDQMPSV
A0A1R3J198 102-175 None
A0A817B9W6 107-174 None
A0A5J5V6M8 5-82 None
A0A0D3C7M4 1-51 None
A0A2G3AVC7 105-167 None
A0A1D6Q273 104-182 None
A0A5J5C5G3 179-252 None
A0A821JP84 145-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.