DPCstruct | MC4186

Metacluster Properties and Pfam Annotations

Number of structural domains394
Mean domain length (aa)183 ± 31 aa
Standard deviation of domain lengths30.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.51
Pfam Score92.24
Assigned Pfam label(s) PF02769- PF02142- CL0063- PF21553- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6N0HY22 23-162 None
A0A7M3QC00 4-225 None
A0A7C1VPP2 45-256 None
A0A5B2TRP7 96-289 None
A0A425CBD7 602-789 None
A0A819KX68 1056-1259 None
A0A3T1DJ80 5-150 None
U1PWR8 416-597 None
A0A524P161 66-220 None
A0A7L9C001 32-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.