DPCstruct | MC4186

Metacluster Properties and Pfam Annotations

Number of structural domains394
Mean domain length (aa)183 ± 31 aa
Standard deviation of domain lengths30.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.51
Pfam Score92.24
Assigned Pfam label(s) PF02769- PF02142- CL0063- PF21553- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812V2T4 360-555 None
A0A384YW68 38-264 None
A0A841Q4E7 199-398 None
A0A7R8ZTZ0 20-208 None
A0A845XR16 145-358 None
A0A2H0USP3 7-214 None
A0A319BVR9 807-1013 None
A0A397GY11 90-281 None
A0A6C8G7I5 215-396 None
A0A2V9PDH4 22-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.