DPCstruct | MC4186

Metacluster Properties and Pfam Annotations

Number of structural domains394
Mean domain length (aa)183 ± 31 aa
Standard deviation of domain lengths30.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.51
Pfam Score92.24
Assigned Pfam label(s) PF02769- PF02142- CL0063- PF21553- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7G8FLD8 7-177 SNFEALAQAIQAGTLNARIQRLVVNNPGCGAQQRAERLGIPVSVLDHRLIKDRRKLDGELVRLFRADQVELVVMAGWMRIVTEVLIS…
A0A1G1ZSI4 4-165 LLLGSDNSECEELRRYLFSCGEEVIFSAEKITSEKVREINPDIIISYNYRHILKEDVFLMPILGTINLHISYLPWNRGADPNFWSHL…
A0A7C1AIN5 6-118 None
A0A4R5AES5 260-477 None
A0A2I0GM38 40-240 None
A0A554KCB6 1-214 None
A0A379USD6 147-317 None
A0A0K2MEG0 7-191 None
A0A522EPJ5 9-226 None
A0A6A6L4K4 22-205 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.