DPCstruct | MC41844

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)303 ± 57 aa
Standard deviation of domain lengths56.59
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.98
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.88
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z0GIU7 373-636 RRLPRPGRSPDPQSWCLIAARAPSAHNTQPWEPQLLDDGAEPRIELTVDPARTLPVGDPDHRDLHLSLGAWIESFAVAAAAEGQQVR…
A0A2H0TR66 1-344 MKDIIEKVIAEGICAPSGENKQPWEFYIREDGFDVYNLPNRDVSLYNYAQQGSLMAHGALIENVVLSANANGYEAHIQLFPNHQNEN…
A0A4R2V436 6-254 None
A0A3L7PIM6 29-319 None
A0A7Y3P580 582-950 None
A0A1Z1WQB7 11-195 None
A0A2V7XUB3 100-423 None
A0A158J175 9-329 None
A0A3B9EY57 134-531 None
A0A426H612 202-487 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.