DPCstruct | MC41839

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)95 ± 9 aa
Standard deviation of domain lengths8.61
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score77.02
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)40.43
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453EHY9 36-121 GNWLLPFAGQAYFDAELEAWVGLARDKESSGYLCSCDVPPVAAKLTSPPSWKLGQDKMFSKDSELHRGAKLVYMGDSKFCLIESLF
A0A3B6NND1 2-95 WQLPFTGRGYFDPELDAWVGLSAQLDTIGHICSCDVVSTNSGTSHQQCPAMKVGKENLFSEFPDERHIGATLVYTGGESKLCLLEVI…
A0A446KQ83 216-307 None
A0A4U6SVT5 79-170 None
A0A0D9WXF1 232-326 None
A0A835FBX1 1-98 None
A0A453I9Q5 51-154 None
A0A0D9WX15 212-309 None
A0A3L6T701 236-330 None
A0A1E5VHH1 6-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.