DPCstruct | MC41806

Metacluster Properties and Pfam Annotations

Number of structural domains595
Mean domain length (aa)366 ± 87 aa
Standard deviation of domain lengths87.44
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.87
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.09
Pfam Score94.19
Assigned Pfam label(s) CL0023- CL0270- CL0479- PF06226- PF10283

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A158R4G8 13-406 SFTVPASSIHIIDTPEEFYNCLLELAKNVRNRITLSTLYIGDGPLEQAFVEQLRKSINDNSDLSLEILIDYFRGTRGGEKSSVALLK…
A0A160SYZ4 203-589 PAVITATAALTIAVAPDNAYAVIARAVRAADTSIRLASLTLENMPLAEELAAAARRGVTVTALLEGGPPGGLTDQERAACRIIESAG…
A0A3E1ET85 364-693 None
A0A2H0P7H8 103-458 None
A0A226RWG7 13-312 None
F8CQW7 306-756 None
A0A162KT02 391-717 None
A0A553ML49 49-611 None
A0A3E1ESA8 125-408 None
A0A182TNC9 373-803 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.