DPCstruct | MC41796

Metacluster Properties and Pfam Annotations

Number of structural domains158
Mean domain length (aa)120 ± 20 aa
Standard deviation of domain lengths19.87
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score91.48
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)28.83
Pfam Score84.98
Assigned Pfam label(s) PF10589- CL0344- PF00499- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X6KHZ6 89-216 VPCVRGEKMRDAIMDFDYLRGELGSGLGTAAVIVMDKQTDIIKAIWRLSKFYKHESCGQCTPCREGTGWMMRVMDRLVRGEAELEEI…
M9M1P9 548-680 VPILPKHKCEEVLMDFDSLRENQSSLGTGAVIVMDKSTDVVQAISRFAKFYKHESCGQCTPCREGTTWLANMMERFEEGRGNNREID…
A0A6G3V3I2 2-83 None
R6H7R0 32-129 None
A0A504X706 400-533 None
A0A6A6KX24 139-243 None
A0A3D1R6E8 3-135 None
A0A090MT50 609-738 None
A0A7Y7NWV5 115-233 None
A0A7V4N2J6 2-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.