DPCstruct | MC41764

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)192 ± 40 aa
Standard deviation of domain lengths39.89
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score87.04
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)28.86
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446PI77 1-278 MDSENLHGALSENKVTSALMSIRKALEEQIEESSSRELCILTTLACSEPPLLEETLNRIKVIRELELHGVDDGRRKLYPSAEESLKH…
A0A4E9FQD3 5-186 KVQKVCTTIREHILSLDDIHITDLYTTVILTYLKEQPPQVSKALLALREQSLKLPHGKELEKKWIAYVSLLAPTENLFNVALSTYDL…
E9G9I7 7-169 None
A0A0C9WJQ8 486-639 None
A0A0B1SQ22 59-228 None
A0A428NXR3 32-207 None
A0A058Z1A5 228-509 None
J9F7E9 204-373 None
A0A820ZYA1 146-324 None
Q5KF87 680-846 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.