DPCstruct | MC41756

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)138 ± 12 aa
Standard deviation of domain lengths11.66
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.29
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)40.87
Pfam Score91.13
Assigned Pfam label(s) CL0081- PF05033

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W5MHR5 7-145 YKSPCGLTLRSMSEIERYLFSVHCDFIFLEMFCLDPYVLVDRRFQPQKPSYFISDITEGKEDVPLSCVNEIDVTPPPSVAYSKERIP…
T1K8E0 225-370 EVSYVAPCGRRLRNIEELDKYLSITNCSLSIDYFTFEVYVELYNESGNSRIRCNWLNNDITVGRESKIISAINSCDNVEFPSDFNYI…
A0A2Y9NGA1 173-319 None
A0A3Q0KPQ6 598-741 None
A0A3Q0KQ18 248-391 None
A0A2J8VSC4 176-319 None
A0A183NFE4 2-130 None
A0A6J3EK70 191-337 None
A0A819LK65 667-786 None
A0A669D436 68-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.