DPCstruct | MC41752

Metacluster Properties and Pfam Annotations

Number of structural domains51
Mean domain length (aa)179 ± 32 aa
Standard deviation of domain lengths31.98
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.28
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.19
Pfam Score98.00
Assigned Pfam label(s) CL0020- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W5M2A3 2-196 VKSLVQNPFLYLGSYVRSLVSSIMYCILEPLAASINPLNDHWTLRDYAALLLSHIFWTHGDLVSGLYHQILLSLQKVLSDPVRPLCS…
A0A3P7Y8E1 118-268 RMIRSIAVNKSVKLDGVLHEFLPSLMSCMLGRVLCTRPDSDNHWALRDFAGKTLITIIKDHGTKETKRRSFRAVKRIFDEPSSSYSM…
A0A7R9P4H7 259-409 None
A0A0A9Y0P3 31-256 None
A0A178C7N7 626-788 None
A0A7S3F9E4 6-163 None
A0A3R7IA57 678-840 None
A0A1Y1LHA3 103-325 None
A0A842YZ10 69-233 None
A0A1R0GNQ7 1-145 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.