DPCstruct | MC41628

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)91 ± 13 aa
Standard deviation of domain lengths13.38
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.10
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)57.86
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377C414 1-112 MTNWHQLTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQYIVEDIYVSGVKEENITVVGDATP…
A0A1M6H257 52-117 GMEAVNGFRYRVQEEEMAVAVIDCGGSLRSGVYPRKGIPTINLVPTGKSGPLSEFMTANMYVSGVS
A0A2X1QSL1 230-327 None
R2XH40 45-123 None
E2SMN4 80-171 None
A0A3S4GGE1 1-96 None
A0A377VWX7 43-141 None
A0A7V8IJB7 44-127 None
A0A2X2WVC0 43-147 None
A0A7C5E396 81-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.