DPCstruct | MC41592

Metacluster Properties and Pfam Annotations

Number of structural domains602
Mean domain length (aa)168 ± 37 aa
Standard deviation of domain lengths37.14
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.20
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.70
Pfam Score95.49
Assigned Pfam label(s) CL0137- PF13966- PF00689- PF00122- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DS89 12-231 None
A0A438I313 4-132 None
A0A076H4A1 177-307 None
Q14QL3 163-326 None
A0A835MFP5 213-450 None
A0A2S2NE80 178-371 None
A0A813C2V6 8-116 None
A0A5N4DTJ3 476-658 None
A0A2R6BB62 106-257 None
A0A6A5ASH8 151-340 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.