DPCstruct | MC41592

Metacluster Properties and Pfam Annotations

Number of structural domains602
Mean domain length (aa)168 ± 37 aa
Standard deviation of domain lengths37.14
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.20
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.70
Pfam Score95.49
Assigned Pfam label(s) CL0137- PF13966- PF00689- PF00122- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A417BXV7 691-803 None
A0A175VN05 762-951 None
A0A819EQR4 139-336 None
A0A5A8EPR9 79-247 None
M1FVU8 86-216 None
A0A0F4GFY5 30-272 None
A0A2G9S134 54-240 None
A0A5K3ELQ6 314-502 None
A4HU10 1801-1970 None
A0A183KNQ2 35-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.