DPCstruct | MC41592

Metacluster Properties and Pfam Annotations

Number of structural domains602
Mean domain length (aa)168 ± 37 aa
Standard deviation of domain lengths37.14
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.20
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.70
Pfam Score95.49
Assigned Pfam label(s) CL0137- PF13966- PF00689- PF00122- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846KPK3 4-103 None
A0A2H9TG76 709-901 None
A0A2H9THT6 106-307 None
A0A4R1QLP9 102-232 None
A0A418B911 4-163 None
A0A376VPF2 14-124 None
A0A0G4KD41 300-493 None
A0A6A4VRR7 80-274 None
U6K070 405-562 None
U6K5N1 26-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.