DPCstruct | MC41592

Metacluster Properties and Pfam Annotations

Number of structural domains602
Mean domain length (aa)168 ± 37 aa
Standard deviation of domain lengths37.14
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.20
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.70
Pfam Score95.49
Assigned Pfam label(s) CL0137- PF13966- PF00689- PF00122- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445AUT8 645-824 None
A0A831KJG4 48-232 None
A0A2K0WAY8 1-135 None
A0A5J4WMA0 188-404 None
A0A7S1KP62 108-330 None
A0A7J6PNU3 608-842 None
A0A7C1EC03 224-385 None
A0A1Y1V6J7 724-922 None
A0A395IMF3 128-332 None
A0A6A3AUX2 317-524 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.