DPCstruct | MC41592

Metacluster Properties and Pfam Annotations

Number of structural domains602
Mean domain length (aa)168 ± 37 aa
Standard deviation of domain lengths37.14
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.20
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.70
Pfam Score95.49
Assigned Pfam label(s) CL0137- PF13966- PF00689- PF00122- CL0197

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V0QD05 25-186 HPKILFEIRDQENNKQFEVLKVFEFESHLQRMSVIVYDVKGSKYYIYTKGAYEVIEKITGKNQNLQFSNNLLDSLSLQGLRVLATSY…
A0A453BA03 5-128 YEILDILEFTSDRKRMSIVISDSQSGKIFLLSKGADEAILPLAYCGQQIKTFVDAVDKYAQLGLRTLCLGWRELSLEEYLEWSRLFK…
A0A6A6LLM8 59-269 None
A0A6I9YMN3 136-319 None
A0A444WPD7 137-237 None
A0A7C3CQL3 584-717 None
A0A2N9I3T5 64-226 None
A0A1Y2HCR9 619-838 None
A0A820DZM5 144-381 None
A0A0D8XA36 221-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.