DPCstruct | MC41467

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)281 ± 39 aa
Standard deviation of domain lengths39.16
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.27
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)24.63
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A212DPC1 2-296 TRLAEQMHSAFRQWRWREPLEDATLRNVVALASVRPPTFRAPIHPDLAAFTASSGHDVTQDIATDVLSGEWFADKSLFHVKSENFGF…
A0A6N7FDT3 13-234 TLESYYLRRDNFGFAAPKGTVAIVEAEPLPVADRRLVIARHGQDTYARRLLRSNDSTLIGLTAETPDPRRSPKTKFLPESEVALHQV…
A0A1I4B3S5 161-395 None
A0A149S9P9 175-478 None
A0A853I4R5 1-195 None
A0A259LP47 403-706 None
A0A512IP88 15-290 None
A0A418SJM1 824-1133 None
A0A7S7THI6 476-780 None
A0A2S8GQA1 983-1249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.