DPCstruct | MC41459

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)155 ± 24 aa
Standard deviation of domain lengths23.89
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score69.13
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.83
Pfam Score100.00
Assigned Pfam label(s) PF14901

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I8NWQ6 14-179 NEFLARLQDDLKEAMNTMVCSRCKGKHRRFEMEREPHSARYCAPCSRLHPATEGDLWAESSLLGLKITYFALMDGKVYDITEWAGCQ…
A0A091E3N9 100-232 LSKLQDDLKEAMNTMMCSQCQGKHRRFEMDWEPKNSRYCAECNKLHPAEERDFGAESSMLGLKIAYFALMDGKVYEITEGTGCQCMG…
A0A6J2G7R1 290-468 None
A0A0B1T5J8 2-133 None
M4EB72 284-411 None
A0A443Q413 179-286 None
J9E926 5-171 None
A0A1D6GDW4 217-412 None
A0A3S3QFA2 1-138 None
A0A6P5G470 484-632 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.