DPCstruct | MC41458

Metacluster Properties and Pfam Annotations

Number of structural domains169
Mean domain length (aa)100 ± 15 aa
Standard deviation of domain lengths15.24
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score79.75
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)22.92
Pfam Score93.62
Assigned Pfam label(s) PF02563- CL0072- CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V6JHE8 20-117 PQLELFRQNYQYRIGVGDVLNVTVWDHPELTTPAGQYRSASDTGNWVHTDGSIFYPYIGRLQVAGKTLEEVRSLIAARLAEVVENPQ…
A0A7C0WND8 25-98 RKYTLGPDDAVRVVVRNHPEFDFGAMVEEGGELVIPLTNEIMQADGLTRDELAETIRQYLTAYIDNPFVSVFIT
A0A1V5FRN5 76-172 None
A0A517NX46 57-182 None
A0A081BTC4 14-112 None
B9X9K9 721-836 None
A0A419DUQ8 13-100 None
A0A1G1AGP4 291-394 None
F8J9B7 42-157 None
A0A849GJM3 6-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.