DPCstruct | MC41396

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)130 ± 9 aa
Standard deviation of domain lengths9.32
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score82.80
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)50.12
Pfam Score100.00
Assigned Pfam label(s) PF19422

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P5Z7W7 334-454 VTNGLCRLFRSRRVLSYSYPFAFYMFGEELFKDEMTNEEREMKQHLFEDQQQQLEANVEKLSKFLEEPFDQYPDDKVMEIRMQVINL…
A0A4U6TA05 227-346 VINGLNRLFRSRRVLSYSYPFAFYMFGDEIFKDEMTPEERELKQNLFEDQQQQLEFNVERLSGFLEKDFQNFTDDEVMDTMKHVINL…
A0A287WS25 44-184 None
A0A218XH38 1-145 None
A0A2U1Q733 36-165 None
A0A7J7D324 397-517 None
A0A446R6B6 132-261 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.