DPCstruct | MC41376

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)193 ± 24 aa
Standard deviation of domain lengths24.49
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.94
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.22
Pfam Score100.00
Assigned Pfam label(s) CL0061

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M5X214 1-252 MWETVARDDDPFICCNFIPLDLKELQEKGFSFKTQQDVHDYIKKHIIGKPNEQLVKNVHKEIDFLGIVGPDALINSFTVNCKGQSTG…
L8WH82 174-351 WATMDMDDSSLIVVPLKAIPAERQQLGQDAIRKQREYIRDTIVNRPNEELVQDAKAMSLLHEMVSDLSINAFACNFRLPNGEVNSDV…
A0A2I2GMI9 512-686 None
A0A1J9RPZ9 562-773 None
A0A7M5UXP6 440-665 None
A0A7M5V8V5 1-156 None
F8NVA3 451-584 None
A0A0F0IE73 152-354 None
A0A3C0I1K6 299-474 None
A0A397V2X7 228-409 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.