DPCstruct | MC41314

Metacluster Properties and Pfam Annotations

Number of structural domains4159
Mean domain length (aa)306 ± 55 aa
Standard deviation of domain lengths55.26
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.55
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.31
Mean intra-cluster sequence similarity (%)11.60
Pfam Score96.62
Assigned Pfam label(s) PF16153- CL0094- CL0268- PF07595- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H4TMB9 1-331 None
C7R269 100-512 None
A0A4R4Q9Y0 22-351 None
A0A4R4QEX6 629-1027 None
A0A2Z4L5Q1 93-348 None
A0A2Z4L5S7 49-338 None
A0A2Z4L5U1 6-339 None
A0A2Z4L630 354-704 None
A0A2Z4L7L1 2-219 None
A0A7J4NLD1 357-667 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.