DPCstruct | MC41282

Metacluster Properties and Pfam Annotations

Number of structural domains490
Mean domain length (aa)308 ± 58 aa
Standard deviation of domain lengths58.24
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.21
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)14.81
Pfam Score79.50
Assigned Pfam label(s) CL0023- PF13195- CL0236- PF20073- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5P1FA92 52-319 IPDVIMEGLSRKNYAEFFSTLLAVEEIHLEEEMRTHDMELVTMKRRGNHFLSLEVPGLAEKRPSLVYGDYIFAKLVVPYSNDNKTYQ…
A0A1G9IIB1 33-365 LPEDREQWTDDHYLWELVFQLLDFHRRADKPVWWAMFARQEMTEEELIDDPECIGGMEAAPEHPPEAVKQSSVYTFRYPEQEFKLKV…
A0A7R9P053 354-655 None
A0A6I8V255 640-1014 None
A0A2B4SB46 337-657 None
E9FRA5 206-601 None
A0A4Q7WG60 1-201 None
A0A370PGA2 29-384 None
H3B0T4 432-756 None
A0A446PGS0 186-503 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.