DPCstruct | MC4127

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)88 ± 11 aa
Standard deviation of domain lengths11.08
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.37
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)24.30
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A246JWU5 41-115 AIDIHVAHIDHREGVNLYAAVSRETLMREIAEFCREYWSEIAHDRDPDTLDDEDIARIYFELHPDEYLQTDRVAI
A0A1H8PND8 8-87 IYGFLMTDTIYIAVYRHRHGEDIYAYATEAAALKARDDLANEQWKCEIEGKREPKQKIGERYFGLVEDEKFEIPKRVVLA
A0A7I7SBX6 2-82 None
A0A2D8QZY4 137-238 None
A0A3L7T967 15-104 None
A0A418L5I3 93-182 None
A0A5B9YV61 33-115 None
A0A495QWZ0 52-148 None
A0A0J6T4Z8 104-190 None
A0A4P6FXS4 174-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.