DPCstruct | MC41222

Metacluster Properties and Pfam Annotations

Number of structural domains95
Mean domain length (aa)248 ± 62 aa
Standard deviation of domain lengths61.51
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score80.31
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)25.12
Pfam Score73.37
Assigned Pfam label(s) CL0486- CL0077- CL0635

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q0ILS3 12-300 PICSMHGLAVTTVEGIGSTKTKLHPVQERLAKAHGSQCGFCTPGIVMSMYALLRSLPGKPTMKDMEVALQGNLCRCTGYRPILEGFK…
A0A3M5JR43 33-310 PGTKEGCASGDCGACTVVVGELHSDADGKQTLRYRSLNSCLTFMASLHGKQLISVEDLKHQGQLHSVQQAMVECHGSQCGFCTPGFV…
A0A812ZMB1 283-619 None
A0A653C4B2 133-330 None
A0A2A2KP58 63-317 None
A0A1R1SAK1 59-222 None
A0A388LDW1 2-416 None
A0A7R9B0P5 293-608 None
A0A356KVE4 19-201 None
A0A446M8Y5 5-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.