DPCstruct | MC412

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)89 ± 9 aa
Standard deviation of domain lengths9.29
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score82.16
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R7KQV6 283-362 YRRQRKADMAFEDYDFGANIVEDMSGWEYVNDAREMIRLVFFENRADPDQDSLKGSFTVLFEKNSDEIASVSADIDGYVF
A0A177ID56 18-102 ESRHVAADAKFEAFDFGSSNVVEDAEGWEYFNDGDEMTRTVYFENAENPEADSQRGHFTVRFEEGTDAIAEAYGTLGGAILDDLR
A0A6P1Q7V2 18-97 None
A0A1I7KCD4 88-175 None
A0A2D8QZX6 213-325 None
A0A0E3BG33 223-321 None
A0A1C7LKK5 4-91 None
A0A250LLF1 89-191 None
A0A4Q2VE83 2-87 None
A2SN63 2-88 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.