DPCstruct | MC41188

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)113 ± 11 aa
Standard deviation of domain lengths11.45
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score87.14
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)14.46
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A243HDL0 124-228 KYTYEFYRDGLGGLRIRLPKEISIISHFLEDILDDEADEYIQILDKVVDQKVPQYEIEGNVAAVYIEPNYTSAINLFMSAPNNQCKI…
A0A315EM01 3-131 LRCFIQTQAPIPGSGAQPVRYPACEWVDDDGAADPQHPLNRFVCSWLTSDVNTVERCQEVLDAIAQIEAGQRTQWFADGDAFGVDFS…
A3D0Q3 73-191 None
A0A2T6ERF6 4-93 None
A0A2G6PK17 1-124 None
G6F245 2-118 None
A0A3N1PFL4 1-114 None
A0A1M4UCJ4 3-128 None
A0A1E5KZ49 3-120 None
A0A2T6A491 5-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.