DPCstruct | MC41006

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)297 ± 49 aa
Standard deviation of domain lengths48.97
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.14
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.85
Pfam Score87.85
Assigned Pfam label(s) CL0488- PF04314- CL0430- CL0308

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A3YFE1 7-243 LRLLTWASGAWTVLAAANLIVAAPESNGVELGRLLEPGAFGPLYTFGYMPRAWTVTLFGALVLWLCSYWGTRWTTLLPGLWAGIIGA…
A0A6J6RV06 2-322 YLSALLAAGVAFFLAFLHDQADDRWRIVPIVRIGSFLAVVGALGIVMSQAALLTGKGAGAITDTKVLRNVLTENLGWSLALLMIGLA…
A0A2V6QM24 4-319 None
A0A411YBK2 346-625 None
A0A7C2IC53 5-353 None
A0A838H3M0 98-445 None
A0A419HGE1 143-425 None
D3PYY3 574-869 None
A0A522SCN9 2-358 None
A0A2V6IHP0 4-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.