DPCstruct | MC40970

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)236 ± 18 aa
Standard deviation of domain lengths18.10
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score78.69
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)37.17
Pfam Score91.11
Assigned Pfam label(s) CL0123- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835HKD4 46-288 TFPESCRMLMDELVSITYKYGDERTKVRALLCDIYHHAIMDGFSESRDLLLMTHLQDGVQHMDISTQILFNWAMAQLGLCAFRVGLV…
A0A835H4R5 1-223 MLFAIYHHAINDEFSVSRDLLLMSHLQDKVQHLDASTKILFNRTMAQLGLCAFRAGLIAEAHSYLSELYADGSIKKLLCQGVSDCSC…
A0A7J9IPI3 155-388 None
C5L9H5 58-305 None
A0A376B2L8 523-788 None
A0A7J5Z1G6 348-567 None
A0A820XGB2 75-308 None
D8R7V3 2-188 None
A0A7J6P0B7 633-867 None
A0A7J8LE24 100-350 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.