DPCstruct | MC40874

Metacluster Properties and Pfam Annotations

Number of structural domains109
Mean domain length (aa)128 ± 20 aa
Standard deviation of domain lengths20.18
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score90.83
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)18.41
Pfam Score61.11
Assigned Pfam label(s) CL0175- PF03243- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3M0XJC6 8-127 IAYGGEQQKRCPICGMLLKGNENTAFVIEWKNGDETTYCCPHCGLWVVAQGDERILFAKTRDFISGEWVDAKKAFYLFNSKAVPACS…
A0A432SK42 30-145 MFCTECGMNLPMFYKTNHAADVDGKVKQYCSIHCLVEDKEKNGKDLKNIRVVDVQTLKFIPVEKATYVVGSSVKGTMSMTSKYAFAD…
A0A3A4ZVW4 94-223 None
A0A7X2IL31 21-142 None
A0A833H3Q6 45-191 None
A0A558DAK8 17-146 None
U1QMF4 34-196 None
A0A7C5N1G7 189-323 None
A0A1I6UTC8 269-379 None
A0A3M1G3Y5 4-125 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.