DPCstruct | MC40831

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)321 ± 56 aa
Standard deviation of domain lengths55.51
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score65.50
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.22
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)21.78
Pfam Score78.95
Assigned Pfam label(s) CL0123- PF12253- PF15539

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q2X8U2 14-277 RKLYGTMKLLLFHENHRPAYWGTWRKTSLHISPRCPLRKDTDLLDYEVDSDEEWEEEEPGESLSHSEGEDEDEGGEDDDDNDGFFVP…
A0A1X2IGP8 37-355 IDHSPEEFDDQLRRRYLQELTTKRQELTFPRRIKRKVDLKQLLLPGTTGSNLDAIHRPENKSLLKMKLLQFTEDVRPAYYGTWTKSS…
Q6C0U7 142-504 None
A0A0C2I5X3 107-385 None
J5RFD0 194-588 None
A0A146H6I6 342-736 None
A0A3N4IQ31 28-344 None
A0A1X0RRQ7 3-261 None
A0A310SQY2 1-326 None
T1JHB3 314-670 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.