DPCstruct | MC40826

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)157 ± 17 aa
Standard deviation of domain lengths16.78
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score73.80
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.17
Pfam Score46.67
Assigned Pfam label(s) PF08633- PF10278

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X2HXD0 6-138 TGGTDLLTYYDLVSCYKKYINQTIDPTLSSFVADLPGKTTVEADGYMLHLLRDPHIEQDSGNSIQPLDSITLKDAYQLKEGPVPGFD…
S9X4L1 1-138 MPESPKYHYVGSTQFQPVKPSPHENLTELYGLTELAKKVGRIDEHGNKRKMRRSYKAYIQDLPGQNEIIKDDTLKQWLVNPIMEDVP…
A0A1E3NJV0 2-151 None
G4VKK2 51-203 None
A0A5J4ND20 54-202 None
A0A1E3QCG0 1-185 None
A0A060T3X3 1-193 None
K1WZ79 97-258 None
A0A1Y2FIV7 1-162 None
A0A1U7LKJ0 62-205 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.