DPCstruct | MC408

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)159 ± 22 aa
Standard deviation of domain lengths21.82
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.78
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)23.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3A8APE0 9-162 LAAGHAHAAESVYTTLDLDACAVLDQDDESGGISLQCDGLPGHPVFASEGDLRFDVDYGVPNDRWESFGPFNSVNQTVEWRVVDGLP…
A0A1F9GN37 13-166 ESIYTDLKGKACKLVWQHEITGDTESECPGVGGNKLIVEDHDVRMSVTVIDPQGEKHRLNYYHTISRGTFSELGSKAEWMVQKKGNQ…
A0A6I4TXH0 3-115 None
A0A1E3WB28 3-136 None
A0A5C7UZX0 3-185 None
A0A2S3UY97 104-277 None
A0A178I388 1-150 None
A0A7W8X8W5 14-184 None
A0A5N7MNQ3 191-356 None
A0A7W9A243 9-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.