DPCstruct | MC40778

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)148 ± 16 aa
Standard deviation of domain lengths15.58
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.87
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.51
Pfam Score74.54
Assigned Pfam label(s) PF16350- CL0063- CL0289

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0K2QW31 301-453 VTHSAGIARAVAELLTTGKSSIDLGDCDIHRFEEVQLTPEYVSETSQQNFVEIYDVLHPLQPKLSPRNLRVSPFHARHKQLGGYFLE…
A0A6J1WVA7 4-170 YHVAAGMKTVGISAAGGVAEATVDSIVDGYTKYDMYELDINRFLGLHNNKRFLRDRVKEVPSVHYGLPYPFHEFETGRNLRLSPIYP…
A0A212DU43 17-166 None
A0A212DUK1 78-210 None
A0A1I8IES6 55-199 None
A0A5N5TIX1 68-224 None
A0A7R9JL90 65-194 None
A0A6J0Z3M8 522-665 None
A0A7R9FP97 116-265 None
A0A1I7WRY2 257-406 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.