DPCstruct | MC40759

Metacluster Properties and Pfam Annotations

Number of structural domains133
Mean domain length (aa)174 ± 33 aa
Standard deviation of domain lengths33.43
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.11
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)22.15
Pfam Score94.68
Assigned Pfam label(s) CL0634- PF01627- CL0025

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V6NFL1 1-195 MSMDISAFYQTFFDEAAELLADMEQHLLILDPENPDSEQLNAIFRAAHSIKGGAGTFGFTVLQETTHLLENLLDEARRGEMALSTAI…
A0A2X2DH19 2-118 KADELLADMEQHLLLLDPQNPDQEQLNAIFRSAHSIKGGAATFGFVKLQQTTHVLENLLDSARRHEMVLTDDIINLFLEAKDIMQQQ…
N6VYP0 1-179 None
A0A2T6CKK7 206-375 None
A0A536VXV4 681-871 None
A0A7J0BJ14 4-244 None
A0A520D2G1 2-148 None
A0A4Q6G8E8 4-184 None
A0A2X2S420 9-201 None
A0A2G6EKA8 9-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.