DPCstruct | MC40686

Metacluster Properties and Pfam Annotations

Number of structural domains2587
Mean domain length (aa)226 ± 46 aa
Standard deviation of domain lengths46.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.81
Pfam Score79.42
Assigned Pfam label(s) PF01594- CL0020- CL0398- CL0263- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F0YET4 113-364 None
T0KBA9 25-257 None
L7UIC4 428-655 None
A0A1C4RI99 2-138 None
A0A6P8H014 31-180 None
A0A444U9Z0 2-187 None
D5MGW3 176-400 None
A0A7C4ZGM5 29-272 None
A0A7Y2FDA0 200-428 None
A0A2E3J202 23-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.