DPCstruct | MC40686

Metacluster Properties and Pfam Annotations

Number of structural domains2587
Mean domain length (aa)226 ± 46 aa
Standard deviation of domain lengths46.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.81
Pfam Score79.42
Assigned Pfam label(s) PF01594- CL0020- CL0398- CL0263- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821A2E3 243-474 None
A0A4C1UHA6 1-357 None
A0A7G5LXH2 112-340 None
A0A7V4HGA5 4-172 None
A0A1I0QGW2 214-572 None
A0A835R567 394-618 None
A0A1I2T7Y1 5-182 None
A0A7J9ZVR3 24-271 None
G0QGW9 8-221 None
A2YH33 166-414 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.