DPCstruct | MC40686

Metacluster Properties and Pfam Annotations

Number of structural domains2587
Mean domain length (aa)226 ± 46 aa
Standard deviation of domain lengths46.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.76
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.81
Pfam Score79.42
Assigned Pfam label(s) PF01594- CL0020- CL0398- CL0263- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K1IK41 544-797 None
A0A845GSS7 119-390 None
A0A1I8QF31 311-519 None
A0A2A2JVX8 113-304 None
A0A417CVN5 35-219 None
A0A6A5HMG9 557-718 None
A0A2V8MXB0 205-495 None
A0A5B7FST9 4-196 None
A0A537YUI6 11-249 None
F9PVL4 33-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.